To begin a relationship or close association with someone, often disapprovingly.
"His parents were worried he had taken up with a group of older kids who were skipping school."
To begin associating with someone (often disapprovingly), or to raise a matter with the appropriate person.
To start spending time with someone (often in a way others disapprove of), or to go and complain about something to the right person.
2 meanings, ordered from most common to least. Color-coded by CEFR level.
To begin a relationship or close association with someone, often disapprovingly.
"His parents were worried he had taken up with a group of older kids who were skipping school."
To raise a problem, complaint, or issue with the relevant person or authority.
"If you're unhappy with the billing, you should take the matter up with the customer services department."
The 'associate with' sense often implies parental or social disapproval ('she's taken up with a bad crowd'). The 'raise a matter' sense is more formal and common in British English administrative contexts. These two senses are distinct enough that context is essential.
Natural word combinations native speakers use most often.
The five tense forms you'll use most often.
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